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1

Determination of lipophilicity and its use as a predictor of blood–brain barrier penetration of molecular imaging agents

Rikki N Waterhouse

Journal:

Molecular Imaging and Biology

Year:

2003

Language:

english

File:

PDF, 216 KB

english, 2003

2

Synthesis and in vivo evaluation of [11C]zolpidem, an imidazopyridine with agonist properties at central benzodiazepine receptors

Filip Dumont, Rikki N. Waterhouse, Julie A. Montoya, Filomena Mattner, Andrew Katsifis, Lawrence S. Kegeles, Marc Laruelle

Journal:

Nuclear Medicine and Biology

Year:

2003

Language:

english

File:

PDF, 73 KB

english, 2003

3

Synthesis of 1-(trans-[123I]Iodopropen-2-yl)-4-(4-cyanophenoxy-methyl)piperidine: A selective sigma receptor radioligand for SPECT

Rikki N. Waterhouse, T. Lee Collier, Joanne C. O'Brien

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1996

Language:

english

File:

PDF, 604 KB

english, 1996

4

Synthesis of a selective sigma receptor radioligand for SPECT: [123I]-1-(2-hydroxyethyl)-4-(4-iodophenoxymethyl)piperidine

Rikki N. Waterhouse, T. Lee Collier, J. C. O'Brien

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1996

Language:

english

File:

PDF, 507 KB

english, 1996

5

Synthesis of [18F]-1-(3-Fluoropropyl)-4-(4-cyanophenoxymethyl)-piperidine: A potential sigma-1 receptor radioligand for PET

T. Lee Collier, Joanne C. O'Brien, Rikki N. Waterhouse

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1996

Language:

english

File:

PDF, 467 KB

english, 1996

6

Synthesis of [123I]-8-[4-[2-(5-iodothienyl)]-4-oxobutyl]-3-methyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one: A potential dopamine D2 receptor radioligand for SPECT

Rikki N. Waterhouse, J. Timothy Gotsick, George W. Kabalka, Mark M. Goodman, J. C. O'Brien

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1998

File:

PDF, 562 KB

1998

7

Radioiodinated (+)-4-[(αR)-α-[(2S5R)-4-(iodopropen-2-yl)-2,5-dimethyl-1-piperazinyl]-3-hydroxybenzyl]-N,N-diethylbenzamide: a potential ligand for in vitro and in vivo investigations of δ-opioid receptors

Rikki N. Waterhouse, Michael J. Campa, Jason Park, Edward F. Patz

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1998

File:

PDF, 617 KB

1998

8

Synthesis and in vitro Evaluation of N,N′-Diphenyl and N-Naphthyl-N′-phenylguanidines as N-Methyl-D-aspartate Receptor Ion-Channel Ligands.

Filip Dumont, Abida Sultana, Rikki N. Waterhouse

Journal:

Year:

2002

File:

PDF, 28 KB

2002

9

Synthesis of [11C] N-(2-chloro-5-thiomethylphenyl)-N′-(3-methoxyphenyl)-N′-methylguanidine ([11C]GMOM): a candidate PET tracer for imaging the PCP site of the NMDA ion channel

Rikki N. Waterhouse, Filip Dumont, Abida Sultana, Norman Simpson, Marc Laruelle

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2002

Language:

english

File:

PDF, 109 KB

english, 2002

10

Synthesis of [18F]3-[1-(3-fluoropropyl)-(S)-pyrrolidin-2-ylmethoxy]pyridine ([18F]NicFP): a potential α4β2 nicotinic acetylcholine receptor radioligand for PET

Filip Dumont, Abida Sultana, Andrew Balter, Rikki N. Waterhouse

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2003

Language:

english

File:

PDF, 102 KB

english, 2003

11

Radiosynthesis and in vivo study of [18F]1-(2-fluoroethyl)-4-[(4-cyanophenoxy)methyl]piperidine: a promising new sigma-1 receptor ligand

Jun Zhao, Raymond Chang, Patty Carambot, Rikki N. Waterhouse

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2005

Language:

english

File:

PDF, 124 KB

english, 2005

12

Novel PET and SPECT radioligands for visualization of diseased regulatory pathways in breast carcinoma

Christophe Van de Wiele, Alberto Signore, Rudi Andre Dierckx, Rikki Waterhouse, Anna Kolindou, Slegers Guido, Francesco Scopinaro

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Year:

2003

Language:

english

File:

PDF, 114 KB

english, 2003

13

Synthesis and in vitro evaluation of N,N′-diphenyl and N-naphthyl-N′-phenylguanidines as N-methyl-d-aspartate receptor ion-channel ligands

Filip Dumont, Abida Sultana, Rikki N Waterhouse

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 99 KB

english, 2002

14

[123I]TPCNE—A novel SPET tracer for the sigma-1 receptor: First human studies and in vivo haloperidol challenge

James M. Stone, Erik Årstad, Kjell Erlandsson, Rikki N. Waterhouse, Peter J. Ell, Lyn S. Pilowsky

Journal:

Year:

2006

Language:

english

File:

PDF, 244 KB

english, 2006

15

In vitro and in vivo binding of neuroactive steroids to the sigma-1 receptor as measured with the positron emission tomography radioligand [18F]FPS

Rikki N. Waterhouse, Raymond C. Chang, Nana Atuehene, Thomas Lee Collier

Journal:

Year:

2007

Language:

english

File:

PDF, 251 KB

english, 2007

16

SNIDD Special Issue

H. Donald Burns, Richard A. Frank, Rikki Waterhouse

Journal:

Molecular Imaging and Biology

Year:

2005

Language:

english

File:

PDF, 164 KB

english, 2005

17

Preclinical Acute Toxicity Studies and Dosimetry Estimates of the Novel Sigma-1 Receptor Radiotracer, [18F]SFE

Rikki N. Waterhouse, Jun Zhao, Michael G. Stabin, Hanna Ng, Janice Schindler-Horvat, Raymond C. Chang, Jon C. Mirsalis

Journal:

Molecular Imaging and Biology

Year:

2006

Language:

english

File:

PDF, 278 KB

english, 2006

18

Ex VivoImaging of Pancreatic Beta Cells using a Radiolabeled GLP-1 Receptor Agonist

Brett M. Connolly, Amy Vanko, Paul McQuade, Ilonka Guenther, Xiangjun Meng, Daniel Rubins, Rikki Waterhouse, Richard Hargreaves, Cyrille Sur, Eric Hostetler

Journal:

Molecular Imaging and Biology

Year:

2012

Language:

english

File:

PDF, 953 KB

english, 2012

19

Nuclear Medicine Imaging For Prediction or Early Assessment of Response to Chemotherapy in Patients Suffering From Breast Carcinoma

Christophe van de Wiele, Rudi Dierckx, Francesco Scopinaro, Rikki Waterhouse, Alessio Annovazzi, Anna Kolindou, Alberto Signore

Journal:

Breast Cancer Research and Treatment

Year:

2002

Language:

english

File:

PDF, 90 KB

english, 2002

20

#111 Intraperitoneal lipopolysaccharide produces changes in brain metabolic activity as measured by [18F]FDG in the rat

Gregory H. Pelton, Leon N. Lyazidi, Raymond C. Chang, Davangere P. Devanand, Harold A. Sackheim, Rikki N. Waterhouse

Journal:

Brain, Behavior, and Immunity

Year:

2005

Language:

english

File:

PDF, 66 KB

english, 2005

21

Invited commentary

Rikki N. Waterhouse, Timothy J. McCarthy, T.Lee Collier, H.Donald Burns

Journal:

Molecular Imaging and Biology

Year:

2003

Language:

english

File:

PDF, 55 KB

english, 2003

22

In vivo evaluation of [11C]N-(2-chloro-5-thiomethylphenyl)-N′- (3-methoxy-phenyl)-N′-methylguanidine ([11C]GMOM) as a potential PET radiotracer for the PCP/NMDA receptor

Rikki N. Waterhouse, Mark Slifstein, Filip Dumont, Jun Zhao, Raymond C. Chang, Yasuhiko Sudo, Abida Sultana, Andrew Balter, Marc Laruelle

Journal:

Nuclear Medicine and Biology

Year:

2004

Language:

english

File:

PDF, 272 KB

english, 2004

23

In vivo evaluation of [123I]-4-iodo-N-(4-(4-(2-methoxyphenyl)-piperazin-1-yl)butyl)-benzamide: a potential sigma receptor ligand for SPECT studies

Ludovicus Staelens, Ruth Oltenfreiter, Filip Dumont, Rikki N. Waterhouse, Katia Vandenbulcke, Peter Blanckaert, Rudi A. Dierckx, Guido Slegers

Journal:

Nuclear Medicine and Biology

Year:

2005

Language:

english

File:

PDF, 303 KB

english, 2005

24

In vivo evaluation in rats of [18F]1-(2-fluoroethyl)-4-[(4-cyanophenoxy)methyl]piperidine as a potential radiotracer for PET assessment of CNS sigma-1 receptors

Rikki N. Waterhouse, Raymond C. Chang, Jun Zhao, Patty E. Carambot

Journal:

Nuclear Medicine and Biology

Year:

2006

Language:

english

File:

PDF, 210 KB

english, 2006

25

In vivo evaluation of [11C]-3-[2-[(3-methoxyphenylamino)carbonyl]ethenyl]-4,6-dichloroindole-2-carboxylic acid ([11C]3MPICA) as a PET radiotracer for the glycine site of the NMDA ion channel

Rikki N Waterhouse, Abida Sultana, M Laruelle

Journal:

Nuclear Medicine and Biology

Year:

2002

Language:

english

File:

PDF, 59 KB

english, 2002

26

Preclinical acute toxicity studies and rodent-based dosimetry estimates of the novel sigma-1 receptor radiotracer [18F]FPS

Rikki N Waterhouse, Michael G Stabin, John G Page

Journal:

Nuclear Medicine and Biology

Year:

2003

Language:

english

File:

PDF, 89 KB

english, 2003

27

Evaluation of [3H]LY341495 for labeling group II metabotropic glutamate receptors in vivo

Rikki N. Waterhouse, Mark E. Schmidt, Abida Sultana, Darryle D. Schoepp, William J. Wheeler, P.David Mozley, Marc Laruelle

Journal:

Nuclear Medicine and Biology

Year:

2003

Language:

english

File:

PDF, 121 KB

english, 2003

28

Imaging the PCP site of the NMDA ion channel

Rikki N Waterhouse

Journal:

Nuclear Medicine and Biology

Year:

2003

Language:

english

File:

PDF, 131 KB

english, 2003

29

Synthesis and preliminary evaluation of [123I]1-(4-cyanobenzyl)-4-[[(trans-iodopropen-2-yl)oxy]-methyl]piperidine: A novel high affinity sigma receptor radioligand for SPECT

Rikki N. Waterhouse, Karine Mardon, Joanne C. O'Brien

Journal:

Nuclear Medicine and Biology

Year:

1997

Language:

english

File:

PDF, 722 KB

english, 1997

30

in vivo evaluation of [18F]1-(3-fluoropropyl)-4-(4-cyanophenoxymethyl)piperidine: A Selective sigma-1 receptor radioligand for PET

Rikki Noel Waterhouse, Thomas Lee Collier

Journal:

Nuclear Medicine and Biology

Year:

1997

Language:

english

File:

PDF, 2.01 MB

english, 1997

31

In vivo evaluation of [123I]-8-[4-[2-(5-Iodothienyl)]-4-oxobutyl]-3-methyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one as a potential dopamine D2 receptor radioligand for SPECT

Rikki N. Waterhouse, J.Timothy Gotsick, George W. Kabalka, Mark M. Goodman, J.C. O'Brien

Journal:

Nuclear Medicine and Biology

Year:

1998

Language:

english

File:

PDF, 391 KB

english, 1998

32

Examination of four 123I-labeled piperidine-based sigma receptor ligands as potential melanoma imaging agents: Initial studies in mouse tumor models

Rikki N. Waterhouse, Janette Chapman, Beverley Izard, Angela Donald, Kerynne Belbin, Joanne C. O'Brien, Thomas Lee Collier

Journal:

Nuclear Medicine and Biology

Year:

1997

Language:

english

File:

PDF, 834 KB

english, 1997

33

Acute systemic lipopolysaccharide (LPS) produces regional changes in brain Sigma-1 receptors as measured with [18F]2-Flouropropyl-[(4-cyanophenoxy)methyl]piperidine ([18F]FPS) in the rat

Rikki N. Waterhouse, R.C. Chang, J. Zhao

Journal:

Year:

2006

Language:

english

File:

PDF, 51 KB

english, 2006

34

Acute systemic lipopolysaccharide (LPS) produces regional changes in brain sigma-1 receptors as measured with [18F]2-Flouropropyl-[(4-cyanophenoxy)methyl]piperidine ([18F]FPS) in the rat

Rikki N. Waterhouse, R.C. Chang, J. Zhao

Journal:

Year:

2006

Language:

english

File:

PDF, 51 KB

english, 2006

35

Effect of acute systemic baclofen on amphetamine-stimulated striatal dopamine release as measured in rats with the dopamine D2D3 receptor agonist racer [3H]-(+)-PHNO

Rikki N. Waterhouse, R. Chang, C. Narentzenis, A.A. Wilson

Journal:

Year:

2006

Language:

english

File:

PDF, 53 KB

english, 2006

36

(R)-N-Methyl-3-(3-125I-pyridin-2-yloxy)-3-phenylpropan-1-amine: a novel probe for norepinephrine transporters

Balagopal Lakshmi, Mei-Ping Kung, Brian Lieberman, Jun Zhao, Rikki Waterhouse, Hank F. Kung

Journal:

Nuclear Medicine and Biology

Year:

2008

Language:

english

File:

PDF, 441 KB

english, 2008

37

Halogenated 4-(Phenoxymethyl)piperidines as Potential Radiolabeled Probes for σ-1 Receptors: In Vivo Evaluation of [ 123 I]-1-(Iodopropen-2-yl)-4-[(4-cyanophenoxy)methyl]piperidine

Waterhouse, Rikki N., Mardon, Karine, Giles, Katrina M., Collier, T. Lee, O'Brien, Joanne C.

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 380 KB

english, 1997

38

P4-223 Peripheral lipopolysaccharide (LPS) administration produces anatomically discrete increases in brain activity measured by [18]FDG in the rat and regional blood flow by 15O-water in the human

Pelton, Gregory H., Moeller, Jim, VanHeertum, Ronald, Chang, Raymond C., Michaels, Kristen, Mensh, Brett, Sackeim, Harold A., Waterhouse, Rikki N., Devanand, D.P.

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 326 KB

english, 2004

39

Evaluation of Cu-64 and Ga-68 Radiolabeled Glucagon-Like Peptide-1 Receptor Agonists as PET Tracers for Pancreatic β cell Imaging

Bandara, Nilantha, Zheleznyak, Alex, Cherukuri, Kaavya, Griffith, David A., Limberakis, Chris, Tess, David A., Jianqing, Chen, Waterhouse, Rikki, Lapi, Suzanne E.

Journal:

Molecular Imaging and Biology

Year:

2016

Language:

english

File:

PDF, 3.13 MB

english, 2016

40

Imaging Sigma Receptors: Applications in Drug Development

Lee Collier, Thomas, Waterhouse, Rikki, Kassiou, Michael

Journal:

Current Pharmaceutical Design

Year:

2007

Language:

english

File:

PDF, 246 KB

english, 2007

41

Modulation of Amphetamine-Induced Dopamine Release by Group II Metabotropic Glutamate Receptor Agonist LY354740 in Non-Human Primates Studied with Positron Emission Tomography

van Berckel, Bart N M, Kegeles, Lawrence S, Waterhouse, Rikki, Guo, Ningning, Hwang, Dah-Ren, Huang, Yiyun, Narendran, Rajesh, Van Heertum, Ronald, Laruelle, Marc

Journal:

Neuropsychopharmacology

Year:

2006

Language:

english

File:

PDF, 164 KB

english, 2006

42

Editorial

VAN DE WIELE, CHRISTOPHE, SIGNORE, ALBERTO, SCOPINARO, FRANCESCO, WATERHOUSE, RIKKI, DIERCKX, RUDI ANDRE

Journal:

Nuclear Medicine Communications

Year:

2001

Language:

english

File:

PDF, 51 KB

english, 2001

43

Brain Penetration of the ROS1/ALK Inhibitor Lorlatinib Confirmed by PET

Collier, T. Lee, Maresca, Kevin P., Normandin, Marc D., Richardson, Paul, McCarthy, Timothy J., Liang, Steven H., Waterhouse, Rikki N., Vasdev, Neil

Journal:

Molecular Imaging

Year:

2017

Language:

english

File:

PDF, 361 KB

english, 2017

44

Assessment of Cancer-Associated Biomarkers by Positron Emission Tomography: Advances and Challenges

Collier, T. Lee, Lecomte, Roger, McCarthy, Timothy J., Meikle, Steve, Ruth, Thomas J., Scopinaro, Francesco, Signore, Alberto, Van Brocklin, Henry, Van de Wiele, Christophe, Waterhouse, Rikki N.

Journal:

Disease Markers

Year:

2002

Language:

english

File:

PDF, 1.42 MB

english, 2002